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ASLENE ORLISTAT 120MG

37.76 30.86

Orlistat (Xenical, Alli) is a drug available in prescription and over-the-counter that promotes weight loss. Side effects include abdominal pain and discomfort, oily or fatty stools, gas (flatulence), oily spotting on underwear. Drug interactions, dosing, and pregnancy and breastfeeding safety information should be reviewed prior to taking any OTC or prescription medication.

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What is Orlistat?

Orlistat is a weight loss medication used to assist people who are overweight in reducing their BMI. It is indicated in people with a BMI over 30, or 28 for those with additional risk factors. Orlistat is the generic version of the better-known brand, Aslene. They come in capsule form, and the prescription only version contains 120mg of the active ingredient.

How Does it Work?

Orlistat capsules work by preventing around a third of the fat from the food you eat from being digested. The undigested fat is not absorbed and is passed out with your faeces. Orlistat works in the same way as the over the counter medicine Alli. They contain the same active ingredient (Orlistat), however, the prescription version is twice the strength (120mg instead of 60mg).

Because Xenical is no longer the only manufacturer of Orlistat, this has helped lower the price of the generic form of the drug. By decreasing the amount of fat the body absorbs and improving your diet and exercise routine, it is possible to achieve significant weight loss.

Before using Orlistat or Xenical, you should read the patient information leaflet.

Losing weight with Orlistat

Orlistat helps you avoid gaining weight by reducing the amount of fat absorbed by your body. However, it does not necessarily cause you to lose weight. Therefore, it’s still important to stick to a healthy diet and exercise plan. In combination, the drug can be successful in reducing your weight into a more healthy BMI range.

Orlistat (Xenical) is usually recommended if you have made a significant effort to lose weight through diet, exercise or changing your lifestyle.

Even then, orlistat is only prescribed if you have:

  • a body mass index (BMI) of 28 or more and other conditions related to weight, such as high blood pressure
  • a BMI of 30 or more

Treatment with Orlistat (Xenical) must be combined with a low-calorie diet and other weight loss strategies, such as doing more exercise.

Effectiveness

Orlistat is recommended to be taken over a 12 week period and most people can expect to lose around 5{b1ecc0e6fb758b9859e821939982ded4a150c00bec619071c3e144cc6f78656d} of your original body weight if combined with a good lifestyle and regular exercise. The medication itself should reduce the amount of dietary fat absorbed by your body by around 33{b1ecc0e6fb758b9859e821939982ded4a150c00bec619071c3e144cc6f78656d}, so this gives you a good opportunity to lose weight if you increase the amount of exercise you do.

Orlistat Dosage

The usual dosage of Orlistat is 120mg three times a day (with your meals). As it works to reduce the fat absorbed by your body, you do not need to take a dose if you skip a meal. You also don’t need to take a dose if you have a 0 fat meal, as there will be not fat for the body to absorb!

What is the dosage for orlistat?

  • The recommended prescription dose for Xenical is one capsule (120 mg) three times daily.
  • The recommended dose for alli is 60 mg three times daily.
  • Orlistat should be taken one hour after or during a meal containing about 15 mg of fat. Meals without fat do not require orlistat.
  • No additional benefit has been shown when orlistat was taken in doses greater than 120 mg.
  • Patients should eat a nutritionally balanced, reduced calorie diet that contains approximately 30{b1ecc0e6fb758b9859e821939982ded4a150c00bec619071c3e144cc6f78656d} of calories from fat.
  • alli includes an individually tailored online weight loss support program.

Some dietary vitamins bind to fat (vitamins A, D, E and beta- carotene). When orlistat is taken, these vitamins are not absorbed and are eliminated in the stool in increased amounts along with the fat. Therefore, patients taking orlistat should take a multivitamin containing these “fat-soluble” vitamins to ensure that adequate amounts of the vitamins are available for absorption. To ensure that the vitamins in the multivitamins are not bound to fat like the vitamins in the diet, the multivitamin should be taken at least two hours before or several hours after the orlistat

Which drugs or supplements interact with orlistat?

  • The blood thinning effect of warfarin (Coumadin, Jantoven) depends on the amount of vitamin K in the body, and vitamin K is one of the vitamins that binds to fat. Patients receiving warfarin who begin orlistat should have their blood clotting monitored closely because the orlistat may cause levels of vitamin K to decline. This will increase the effects of warfarin and lead to abnormal bleeding from the warfarin. There is no evidence that a deficiency of vitamin K occurs in patients who are taking orlistat.
  • Orlistat may reduce the absorption and blood levels of cyclosporine (Sandimmune) when both drugs are administered together. Therefore, cyclosporine should be administered two hours before or after orlistat, and more frequent monitoring of cyclosporine levels may be needed.
  • Hypothyroidism
  •  has been reported when orlistat and levothyroxine (Sythroid, Levoxyl, Levothroid, Unithroid) were combined. Patients treated with both orlistat and levothyroxine should be monitored for changes in thyroid function. The orlistat and levothyroxine should be taken at least four hours apart.

Is orlistat safe to take if I’m pregnant or breastfeeding?

  • Safe use of orlistat during pregnancy has not been established. Therefore, orlistat is not recommended during pregnancy.
  • It is not known if orlistat is secreted in breast milk. Therefore, it probably should not be taken by nursing mothers.

What else should I know about orlistat?

What preparations of orlistat are available?

Capsules: 60 mg (alli), 120 mg (Xenical)

How should I keep orlistat stored?

Capsules should be stored at room temperature, 15 C – 30 C (59 F – 86 F)

1 review for ASLENE ORLISTAT 120MG

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